Paula Cannon, Ph.D. is a professor in the Keck School of Medicine of the University of Southern California. She studies genome engineering in hematopoietic stem cells (HSC), with an emphasis on therapies for HIV/AIDS. Dr. Cannon earned a Ph.D. from the University of Liverpool and did post-doctoral training at Harvard and Oxford Universities. In 2010, she first reported on the use of ZFNs to knock out the CCR5 gene in human HSC, which has now led to a clinical trial in HIV-infected individuals. More recently, she has described a platform based on AAV6 that produces high levels of genome editing in HSC, with broad applications for genetic diseases of the blood and immune systems.
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