Take a look at what our speakers have published recently and chat with them about their work in Banff, Canada this coming October.
Mark Davis, Stanford University, USA
Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans.
Variation in the human immune system is largely driven by non-heritable influences.
Michel Nussenzweig, Rockefeller University, USA
Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.
Galit Alter, Ragon Institute, USA
A Functional Role for Antibodies in Tuberculosis.
Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.
Dan Barouch, Ragon Institute, USA
Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys.
Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys.
Luis Barreiro, McGill University, Canada
Social status alters immune regulation and response to infection in macaques.
Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens.
Yasmine Belkaid, NIAID/NIH, USA
Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity.
Commensal-dendritic-cell interaction specifies a unique protective skin immune signature.
Marco Colonna, Washington University, USA
Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells.
Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands.
Eran Elinav, Weizmann Institute, Israel
Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations.
Persistent microbiome alterations modulate the rate of post-dieting weight regain.
Donna Farber, Columbia University, USA
Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life.
Spatial map of human T cell compartmentalization and maintenance over decades of life.
Florent Ginhoux, A*STAR, Singapore
Mapping the human DC lineage through the integration of high-dimensional techniques.
Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.
Adrian Hayday, The Francis Crick Institute, UK
AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies.
Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants.
Antonio Lanzavecchia, IRB, Switzerland
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Mike Lenardo, NIAID/NIH, USA
Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy.
Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.
Mihai Netea, Radboud UMC, The Netherlands
Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.
Host and Environmental Factors Influencing Individual Human Cytokine Responses.
A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.
Virginia Pascual, Baylor Health, USA
Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.
Dana Pe'er, Memorial Sloan Kettering, USA
Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis.
Integration of genomic data enables selective discovery of breast cancer drivers.
Sergio Quezada, University College London, UK
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.
Lluis Quintana-Murci, Institut Pasteur, France
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America.
Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations.
Federica Sallusto, IRB, Switzerland
Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection.
T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.
Shannon Turley, Genentech, USA
Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation.
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.
Eric Vivier, Centre d’Immunologie de Marseille-Luminy, France
Evidence of innate lymphoid cell redundancy in humans.