Dr. Hotamisligil’s research efforts focus on the genetic basis of common and complex diseases, particularly obesity, diabetes, and heart disease. His research examines the molecular mechanisms of nutrient sensing and response pathways as they relate to immunity and physiological metabolic homeostasis. He is an internationally recognized leader with many seminal contributions including the discoveries that defined immunological components of obesity and made significant contributions to the emerging field of immunometabolism. His research group discovered novel hormones as well as lipid chaperones regulating lipid and glucose metabolism, and endoplasmic reticulum as a key organelle regulating cellular and organismic metabolism and immunometabolism, and its role in obesity, insulin resistance, and diabetes. Dr. Hotamisligil pursues interdisciplinary paths, collaborations, and industry alliances towards development of novel preventive and therapeutic strategies against chronic metabolic diseases. These programs have driven several drug development platforms currently in clinical trials. His work has resulted in >185 papers which have received >50,000 citations and resulted in multiple patents.
Dr. Hotamisligil has been recognized with many fellowships and awards from the Markey, Pew, and Sandler Foundations, the American Diabetes Association, the National Institutes of Health and the J.S. Simmons Endowment at Harvard University. He’s an elected permanent member of the Turkish Academy of Sciences and the recipient of the 2004 TUBITAK Science Award. He is an elected fellow of the AAAS and the recipient of the Outstanding Scientific Accomplishment Award of American Diabetes Association, the Wertheimer Award from International Association for the Study of Obesity, the Naomi Berrie Award from Columbia University, Science Award of the Vehbi Koç Foundation, Roy Greep Award of Endocrine Society, and the International Danone Prize. Further information could be obtained at:
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