Tiffany Horng, Ph.D trained in the lab of Dr. Ruslan Medzhitov at Yale University, where she elucidated mechanisms of Toll-like Receptor signal transduction. As an independent investigator at the Harvard T.H. Chan School of Public Health, she pursued studies of inflammasome biology, and more recently, metabolic control of macrophage activation and biology. Her lab showed that metabolic regulators like mTOR and ACLY and metabolic regulation of histone acetylation influence macrophage activation, and are co-opted by the signals that drive macrophage activation for regulation of macrophage biology. In November 2018, Dr. Horng moved her lab to ShanghaiTech University, where she continues to pursue studies aimed at elucidating the etiology and mechanistic basis of metabolic support of macrophage activation.
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