Catriona Jamieson, MD, PhD, is a leader in the cancer stem cell biology field. She is a Professor of Medicine, the Koman Family Presidential Endowed Chair in Cancer Research, the Deputy Director of the Moores Cancer Center and the Deputy Director of the Sanford Stem Cell Clinical Center at the University of California San Diego (UCSD). Jamieson is the Director of the California Institute for Regenerative Medicine (CIRM) Alpha Stem Cell Clinic at UCSD, which provides infrastructure to accelerate the bench to bedside development and implementation of cancer stem cell targeted and cellular immunotherapy trials for hematologic and other malignancies. Dr. Jamieson specializes in myeloproliferative neoplasms (MPNs) and leukemia. MPNs are a family of clonal bone marrow disorders where overproduction of blood cells causes heart attack, stroke, deep venous thrombosis, and pulmonary emboli and can develop into acute myeloid leukemia. Although effective treatments are available, they are laden with serious side effects and patients can become resistant to the treatments. Dr. Jamieson studies MPN cancer stem cells, which can evade chemotherapy and then activate again later, causing disease relapse, progression, and resistance to treatment. Her goal is to find more selective and less toxic therapies for leukemia patients.
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