Dr. Brat received his MD and PhD from the Mayo Medical and Graduate Schools and completed Residency in Anatomic Pathology and a Fellowship in Neuropathology at Johns Hopkins Hospital.
Dr. Brat’s is a practicing surgical neuropathologist with special expertise in neoplastic diseases. He also directs an NIH-funded basic and translational research lab that investigates mechanisms of glioma progression, including the contributions of hypoxia, genetics, tumor microenvironment and stem cells, using Drosophila and mice to model the human disease. He also has an interest in the in silico investigation of brain tumors and has used large-scale clinical and molecular databases, such as The Cancer Genome Atlas (TCGA), to address fundamental questions in human glioma behavior. He has over 18 years of experience in brain tumor research and has written more than 200 peer-reviewed manuscripts and reviews.
Dr. Brat has served in leadership positions that oversee clinical practice and investigation in Oncology and Pathology, including the TCGA Glioblastoma and Lower Grade Gliomas Working Groups; the College of American Pathologists (CAP) Glioma Guidelines Committee; the Executive Council of the American Association of Neuropathologists; the Board of Directors for the Society of Neuro-oncology; the WHO Committee for Classification of Brain Tumors; and the AJCC Expert Panel. He is a member of the American Society for Clinical Investigation.
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