Dr. Li Ding joined the McDonnell Genome Institute at Washington University in 2002. Dr. Ding has extensive experience in cancer genetics/genomics. Dr. Ding’s research focuses on identifying and characterizing somatic/germline genetic changes relevant to cancer initiation and progression as well as drug response by integrating various data types including DNA, RNA, and proteomics data. Dr. Ding is also interested in developing algorithms to facilitate the translation of genomic findings to clinical practice.
Dr. Ding leads the Medical Genomics group, consisting of biologists, bioinformaticians, mathematicians, and statisticians. Dr. Ding’s team has developed a suite of variant detection and interpretation tools including VarScan, SomaticSniper, CMDS, BreakDancer, BreakFusion, PathScan, and MuSiC; many of them are widely used by the research community and have been applied in several large-scale projects such as The Cancer Genome Atlas (TCGA) project and the Pediatric Cancer Genome Project (PCGP).
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