- Richard Kriwacki, St. Jude Children’s Research Hospital, USA
Dr. Kriwacki leads a research group in the Department of Structural Biology at St. Jude Children’s Research Hospital in Memphis, Tennessee, USA, focused on understanding the roles liquid-liquid phase separation in biology and disease. Research areas include the nucleolus and the roles of LLPS in ribosome biogenesis and cellular stress responses, and phase separation by fusion oncoproteins and their roles in oncogenesis. The lab’s experimental approaches range from structural and biophysical methods (NMR, fluorescence spectroscopy, SAXS/SANS, and others) and fluorescence microscopy (confocal and super-resolution) to biochemical and cell biology methods. The lab seeks to understand the molecular details of interactions that underlie biomolecular condensation to form membraneless cellular compartments and how the emergent biomolecular organization facilitates biological processes.
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