Tanja Mittag received her PhD from the Johann Wolfgang Goethe University in Frankfurt, Germany, where she used NMR spectroscopy to characterize multistep protein-ligand binding mechanisms. She trained as a Postdoctoral Fellow with Julie Forman-Kay at the Hospital for Sick Children in Toronto, where she revealed how a highly dynamic complex with several interconverting interfaces can encode a cell cycle switch. In 2010, she joined the Department of Structural Biology at St. Jude Children’s Hospital as an Assistant Member and became Associate Member in 2016. Her lab uses a spectrum of biophysical, biochemical and cell biological tools to elucidate the role of liquid-liquid phase separation for functional compartmentalization in cells, in particular with respect to conformation-function relationships of intrinsically disordered proteins, multivalent protein-protein interactions, and disease processes associated with aberrant phase separation.
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