Tanja Mittag, St. Jude Children’s Research Hospital, USA

Tanja Mittag received her PhD from the Johann Wolfgang Goethe University in Frankfurt, Germany, where she used NMR spectroscopy to characterize multistep protein-ligand binding mechanisms. She trained as a Postdoctoral Fellow with Julie Forman-Kay at the Hospital for Sick Children in Toronto, where she revealed how a highly dynamic complex with several interconverting interfaces can encode a cell cycle switch. In 2010, she joined the Department of Structural Biology at St. Jude Children’s Hospital as an Assistant Member and became Associate Member in 2016. Her lab uses a spectrum of biophysical, biochemical and cell biological tools to elucidate the role of liquid-liquid phase separation for functional compartmentalization in cells, in particular with respect to conformation-function relationships of intrinsically disordered proteins, multivalent protein-protein interactions, and disease processes associated with aberrant phase separation.

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Supporting Publications