Speaker articles

Take a look at what some of our Cell-NCI Symposium: Beyond Cancer Genomics Toward Precision Oncology speakers have published recently and chat with them about their work in Bethesda, USA.

Speakers

Andrea Califano, Columbia University, USA
A modular master regulator landscape controls cancer transcriptional identity

Christina Curtis, Stanford University, USA
Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases

Daniel De Carvalho, Princess Margaret Cancer Centre, Canada
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells

Mathew Garnett, Wellcome Sanger Institute (WSI), UK
Minimal genome-wide human CRISPR-Cas9 library

William Hahn, Dana-Farber Cancer Institute (DFCI), USA
STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells

Cigall Kadoch, Broad Institute/Dana-Farber Cancer Institute (DFCI), USA
A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms

Xiaole Shirley Liu, Dana-Farber/Harvard Cancer Center, USA
Systematic characterization of mutations altering protein degradation in human cancers

Michael McManus, University of California San Francisco (UCSF), USA
Examining the evidence for extracellular RNA function in mammals

Gordon Mills, Oregon Health & Science University (OSHU), USA
Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines

Dana Pe'er, Memorial Sloan Kettering Cancer Centre (MSKCC), USA
Engineering γδT cells limits tonic signaling associated with chimeric antigen receptors

Aviv Regev, Genentech, USA
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

Eytan Ruppin, National Cancer Institute (NCI), USA
Synthetic lethality-mediated precision oncology via the tumor transcriptome

Stuart Schreiber, Broad Institute/Harvard University, USA
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

Louis Staudt, National Cancer Institute (NCI), USA
Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment

Itay Tirosh, Weizmann Institute of Science, Israel
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

Olga Troyanskaya, Princeton University, USA
Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies

Samra Turajlic, The Institute of Cancer Research, UK
Cancer, COVID-19, and Antiviral Immunity: The CAPTURE Study

Jeffrey Tyner, Oregon Health and Science University (OHSU), USA
Ex Vivo Analysis of Primary Tumor Specimens for Evaluation of Cancer Therapeutics

Jonathan Weissman, Whitehead Institute, USA
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts

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