Speaker

Sebastian Amigorena directs the “Center of Immunotherapy for cancers” and the “Immune responses and cancer” Team at Institut Curie (Paris, France), in the "Immunity and Cancer” Department, that he created in 2003 and directed until 2021. His team pioneered the field of antigen cross presentation, establishing the fundamental functional properties of phagosomes in mouse and human dendritic cells and showing how these specializations contribute to the initiation of adaptive immune responses by dendritic cells. More recently, they analyzed the epigenetic programing of T cell differentiation and applied the findings to optimizing CAR-T cell therapies. They also identified a new family of HLA-presented peptides derived from non-canonical splicing events, including in transposable elements and lncRNAs.

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