• Feng Shao, National Institute of Biological Sciences, China
Feng Shao

Professor Feng Shao is an investigator and deputy director at National Institute of Biological Sciences (NIBS), Beijing, and an Endowed Chair Professor of Tsinghua University. Professor Shao’s research lies at the interface between bacterial pathogen and host inflammation. He identified several cytosolic receptors for bacterial molecules, including caspase-11/4/5 for LPS and ALPK1 for ADP-heptose. He discovered the gasdermin family of pore-forming proteins, re-defining pyroptosis as gasdermin-mediated programmed necrosis. His work shows that pyroptosis is a critical mechanism underlying lymphocyte cytotoxicity and tumour immunity. Professor Shao’s work has been recognised by numerous awards, including the Future Science Prize and the William B. Coley Award for Distinguished Research in Basic and Tumour Immunology. He is a member of the Chinese Academy of Sciences and the German National Academy of Sciences Leopoldina, an associate member of EMBO, and a fellow of American Academy of Microbiology and Chinese Academy of Medical Sciences.

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