• Purna Kashyap, Mayo Clinic, USA
Dr. Purna Kashyap

Dr. Purna Kashyap is an Associate Professor of Medicine, Physiology and Biomedical Engineering and the Co-Program Director of the Microbiome program in the Center for Individualized Medicine at Mayo Clinic, Rochester, MN. He is a fellow of the American Gastroenterology Association and member of their Center for Gut Microbiome Education and Research, and serves on the council of American Neurogastroenterology and Motility Society. He is the associate editor of Gut Microbes journal and serves on the editorial board of Neurogastroenterology and Motility and FASEB journal. Dr. Kashyap’s Gut Microbiome Laboratory is interested in understanding the complex interactions between diet, gut microbes, and gastrointestinal function. Deleterious alterations in gut microbiota have been associated with a number of disease states such as Clostridium difficile colitis, functional bowel disorders such as irritable bowel syndrome, and metabolic diseases such as obesity. However, the functional role of gut microbes in the development of these diseases remains largely unknown. To better understand the role of gut microbes, Dr. Kashyap’s laboratory integrates data generated from multi-omic platforms with in vivo and in vitro physiological measurements from human research participants and gnotobiotic mouse models to elucidate interactions among microbiota-derived bioactive molecules and the key regulators of gastrointestinal function. By combining experimental strategies with bioinformatics analysis, Dr. Kashyap's research team hopes to develop novel microbiota-targeted therapies to treat patients with disorders resulting from altered microbiota function.

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