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Cell Symposium: Overcoming Drug Resistance in Cancer
October 25-27, 2020 | Meliá, Sitges, Spain

Resistance to therapy poses a major problem for the successful treatment of cancer, and there is a vast wealth of information emerging in the field of drug resistance to cancer. Today, newly-designed molecular therapies such as immunotherapy, together with improved clinical models and high-throughput screens, are providing an unprecedented understanding of how cancer cells evolve to resist treatment. This exciting and rapidly advancing field therefore demands an opportunity to gather and share key biological advances, as well as to provide a platform for discussion and scientific collaboration, building a path from basic science to translational medicine.

Cell Press is pleased to announce this symposium to discuss the mechanisms by which cancer cells resist therapy, examine ways to overcome resistance, and improve approaches to achieving personalized therapies. Leading experts will present experimental findings from preclinical and clinical studies, and place a spotlight on key outstanding questions.

Our topics will include:

• Resistance: the therapeutic landscape
• Clonal evolution of therapy resistance
• Genetic and epigenetic mechanisms of resistance
• Resistance: metabolic pathways and DNA damage
• Harnessing the tumor microenvironment
• Cancer models, biomarkers and tools to overcome drug resistance .

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  • Iannis Aifantis, NYU School of Medicine, USA
  • Karen Vousden, Francis Crick Institute, UK
  • William D. Figg, National Cancer Institute/NIH, USA
  • Catarina Sacristán, Editor-in-Chief, Trends in Immunology
  • Harmony Turk, Senior Editor, Cancer Cell
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