Ayelet Erez was born in Israel, and completed her medical studies at the Technion Institute in Haifa, Israel. Following her Paediatric Residency, she completed a PhD in Cancer Genetics at Tel Aviv University. She then went to Baylor College of Medicine in Houston Texas, where she trained in Clinical Genetics together with being a postdoctoral fellow focusing on Inborn Errors of metabolism.
Ayelet returned to Israel on 2012 as a senior researcher at the Weizmann Institute of Science in Rehovot Israel, in parallel to working part time as a paediatric cancer geneticist.
In her lab, Ayelet’s research focuses on changes in cancer metabolism through the prism of amino acid homeostasis. She has found that changes in amino acid catabolism contribute to carcinogenesis and can be identified at the genomic and biochemical levels. Furthermore, these changes may be used to predict cancer response to immunotherapy, and may potentially lead to identifiable metabolic alterations that will enable early detection and “personalizing” immunotherapy.
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