Speaker articles

Take a look at what some of our Metabolites in Signaling and Disease speakers have published recently and chat with them about their work in Lisbon, Portugal.

Keynote Speaker

Peter Ratcliffe, University of Oxford, UK
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants


Andrea Ablasser, Swiss Federal Institute of Technology Lausanne, Switzerland
Regulation of cGAS- and RLR-mediated immunity to nucleic acids

Johan Auwerx, École Polytechnique Fédérale, Switzerland
The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Kivanc Birsoy, The Rockefeller University, USA
CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4

Anne Brunet, Stanford University, USA
Linking Lipid Metabolism to Chromatin Regulation in Aging

Jens Brüning, Max Planck Institute, Germany
IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis

Laurent Le Cam, Montpellier University, France
Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53

Judy Campisi, Buck Institute for Research on Aging, USA
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells

Navdeep Chandel, Northwestern University, USA
Mitochondrial complex III is essential for suppressive function of regulatory T cells

Edward Chouchani, Harvard Medical School, USA
New Advances in Adaptive Thermogenesis: UCP1 and Beyond

Heather Christofk, University of California, Los Angeles, USA
Differential Metabolic Reprogramming by Zika Virus Promotes Cell Death in Human versus Mosquito Cells

Ana Domingos, University of Oxford, UK
Obesity: a neuroimmunometabolic perspective

Ayelet Erez, Weizmann Institute of Science, Israel
ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus

Christoph Hess, University of Cambridge, UK, and University of Basel, Switzerland
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2

Jared Rutter, University of Utah, USA
ACP Acylation Is an Acetyl-CoA-Dependent Modification Required for Electron Transport Chain Assembly

Celeste Simon, University of Pennsylvania, USA
Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity

Scott Summers, University of Utah, USA
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

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